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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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C. Combining Tadalafil and Cialis:

Taking Tadalafil and Cialis together can cause a dangerous drop in blood pressure (hypertension), leading to symptoms like dizziness, lightheadedness, or fainting. If you notice any of these effects, contact your doctor immediately.

Ignoring Combination Therapy:

Combining Cialis with other medications or receiving a combination of both can cause complications. For example, you may notice dizziness, lightheadedness, or fainting with these medications. If you think you are shouldering the bill, talk to your doctor.

D.

As with all drug-drug interactions, there are possible drug-drug interactions. It is important for you to tell your doctor about all your prescription and over-the-counter medications you use, especially of blood pressure medications.

E.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read More About Cialis [TUFFER]...

Cialis can cause some side effects. The most common side effects are:

  • Stomach pain
  • Permanent vision loss
  • Sudden headache
  • Suicidalactictusset

Other common side effects include:

  • Breast tenderness
  • Mood changes
  • Headache that can be controlled
  • Decreased libido
  • Erectile dysfunction

If you experience any serious side effects, such as an allergic reaction, groin pain, chest pain, or vision changes that are beyond severe, seek medical attention immediately. This is a condition involving a person’s vision, which may necessitate immediate medical attention.

As with all prescription medications, inform your doctor if you experience any of the following side effects:

  • If you experience any of the following, you should contact your health care provider:
  • If you’re pregnant, could you be pregnant, or can you just for theoplphy?
  • If you have any dietary restrictions, like taking nitrates or nitric oxide donors like amyl nitrite, if you’re taking nitroglycerin, if you’re taking any supplements concerning nitrates, or if you’re taking any medication for high blood pressure. Inform your health care provider if you have a history of heart disease, stroke, low blood pressure, bipolar disorder, or mental illness.

As with all prescription medications, let your doctor know if you have any medical conditions, including a diagnosis of liver disease or kidney disease, a history of heart attack, heart failure, liver disease, kidney disease, or seizures. Your doctor should determine if Cialis is safe and appropriate for you.

In addition, let your doctor know if you are breastfeeding, have any take on conceiveen, or smoke. If you have any existing conditions, discuss them with your health care provider before using Cialis.

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What is Cialis?

Cialis is the brand name of the drug known astadalafil. It is a phosphodiesterase type 5 (PDE-5) inhibitor. It works by helping the body make more blood and oxygen.

Cialis is taken by mouth to treat erectile dysfunction in men. The medication comes in a tablet form, making it easy to swallow.

What is Cialis Used For?

Themedicationis used to treat erectile dysfunction and premature ejaculation. The medication helps improve sexual performance and reduce the amount of time a man is unable to have sex.

What is Cialis Prescribed For?

Cialis is a PDE-5 inhibitor that helps relax the blood vessels in the penis and increase blood flow in the area. This allows the body to achieve and maintain an erection during sexual activity.

Cialis is taken by mouth once a day, approximately 30 minutes to one hour before sexual activity. It may take up to two to four hours to start working.

Cialis is also available in tablet form, usually taken once a day, approximately 30 minutes to one hour before sexual activity. It is taken by mouth, usually one to two hours before sexual activity. It is important to follow the instructions of the doctor or pharmacist if you have questions about Cialis.

Cialis comes in two forms:

  • Tablet
  • Oral pill

Cialis is a prescription medication and should only be taken under the supervision of a healthcare professional. If you are allergic to any ingredient in the medication, including the active ingredient, cialis, it is not recommended for use. If you are taking any other medications, tell your doctor or pharmacist before taking Cialis.

Is Cialis Suitable for Everyone?

It may be an option for patients who prefer a non-pharmacological approach to treatment.

How To Take Cialis?

Follow the instructions for taking aprescription medicationand complete the full course of treatment. Taking Cialis as directed, it is important to follow the prescribed instructions. If you are unsure, speak to your doctor or pharmacist.

Taking the medication as directed will help you get the best results. It is important to take the medication at the same time each day. Taking the medication as directed will ensure that you get the most benefit from it.

Can You Take Cialis?

The following are some common side effects of taking:

  • Nausea
  • Flushing
  • Headache
  • Nasal congestion
  • Blurred vision
  • Dizziness
  • Heartburn

If you experience any of the following side effects, speak to your doctor or pharmacist.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
__US District Court of the Appeals for the District of Columbia

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Cialis interactions
Cialis interaction information

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Drug-food interactions

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Cialis interactions with grapefruit and grapefruit juice

Both Cialis and alpha-blockers can affect the metabolism of tadalafil, a medication used to treat erectile dysfunction. This may enhance side effects or result in increased risk of overdose.